Stem Cell Biology Core Course

Section ID: 82944, Spring 2022

March 29 - June 2, 2022

Course Director, Karl Willert, PhD

Professor of Cellular & Molecular Medicine

The CMM 250 Stem Cell Biology Core Course provides the latest information in stem cell biology, medicine, and ethics.

Course Description

Faculty members from UC San Diego, the Salk Institute, the Sanford-Burnham-Prebys Institute, the Scripps Research Institute, and the La Jolla Institute of Allergy and Immunology will give 1-hour lectures on the basic concepts of embryonic and adult stem cells. In addition, once per week students will present scientific papers that cover some of the recent findings in these rapidly advancing fields of stem cell research.

Scientific lectures

Faculty speakers will present basic, translational, and clinical research findings involving stem cells in human and model systems. Topics will include what is known about various stem cell populations; the identification, purification, and properties of stem cells; possible and actual uses of stem cells in animal models of relevant diseases; possible and actual uses in clinical application to an organ system or disease state. Active participation is encouraged and will be the main criterion for grading.

Course Requirements

Attendance

Attendance is mandatory. You must join the Zoom sessions with your video on. One excused absence will be allowed per quarter.

COURSE SYLLABUS

Syllabus CMM 250
DATE	8:30 am - 9:30 am LECTURE TOPIC/LECTURER (Tue)	9:30 am - 10:30 am LECTURE TOPIC/LECTURER (Thur)
Week 1
March 29, 2022 Tuesday	Course Introduction “Pluripotent stem cells” Karl Willert, Ph.D.	“Growing human organs” Juan Carlos Izpisua Belmonte, Ph.D.
March 31, 2022 Thursday
Week 2
April 5, 2022 Tuesday	“HSC Development” David Traver, Ph.D.	“HSC Maintenance” Robert Signer, Ph.D.
April 7, 2022 Thursday	"Genomics/Transcriptomics/Epigenomics of Substates of Pluripotency" Louise Laurent, Ph.D.
Week 3
April 12, 2022 Tuesday	“Wnt signaling in stem cells” Karl Willert, Ph.D.	“Hippo signaling in stem cells” Kun Liang Guan, Ph.D.
April 14, 2022 Thursday		Sanford Stem Cell Seminar
Week 4
April 19, 2022 Tuesday	“Utilization of Stem Cells in Spinal Cell- Replacement-Based Therapies” Martin Marsala, M.D.	“Generation of functional human brain organoids” Alysson Muotri, Ph.D.
April 21, 2022 Thursday	“Imaging Technologies” Eric Ahrens, Ph.D.	“Building a Lung ”Xin Sun, Ph.D.
Week 5
April 26, 2022 Tuesday	"Using Next-Generation Sequencing to Study Cellular Differentiation and Reprogramming" Chris Benner, Ph.D.	“DNA Modifications and Their Biological Roles” Anjana Rao, Ph.D.
April 28, 2022 Thursday	“Stem Cell Ethics, part 1” Mary Devereaux, Ph.D.	“Stem Cell Ethics, part 2” Mary Devereaux, Ph.D.

cmm 250 syllabus 2022
DATE	8:30 am - 9:30 am LECTURE TOPIC/LECTURER	9:30 am - 10:30 am LECTURE TOPIC/LECTURER
Week 6
May 3, 2022 Tuesday	“Spermatogonial Stem Cells” Miles Wilkinson, Ph.D.	“Trophoblast stem cells and placental development” Francesca Soncin, PhD
May 5, 2022 Thursday	“Liver and Regeneration” David Brenner, M.D.	“Endodermal Progenitors and Modeling Diabetes in a Dish” Maike Sander, M.D.
Week 7
May 10, 2022 Tuesday	“Tissue Engineering” Adam Engler, Ph.D.	Ricardo Zayas, Ph.D.
May 12, 2022 Thursday	“Stem cells, gene therapy and cystinosis” Stephanie Cherqui, Ph.D.	Southern California Stem Cell Series Thorold Theunissen, PhD
Week 8
May 17, 2022 Tuesday	“Stem cells to the rescue: Saving the northern white rhino from extinction” Marisa Korody, Ph.D.	“Clinical development of Beta Cells” Tim Kieffer, Ph.D., Viacyte
May 19, 2022 Thursday	"Genome Engineering: A Primer" Prashant Mali, Ph.D.	“Bio-responsive nano-materials” Ester Kwon, Ph.D.
Week 9
May 24, 2022 Tuesday	“Modeling eye diseases” Karl Wahlin, Ph.D.	“Epidermal stem cells” George Sen, Ph.D.
May 26, 2022 Thursday	“Cardiac Stem Cells” Farah Sheikh, Ph.D.	“Cardiac Tissue Engineering” Karen Christman, Ph.D.
Week 10
May 31, 2022 Tuesday	“Immunologic Consequences of Cellular Reprogramming Processes" Gerald Morris, M.D.	“Bone Stem Cells” Shiri Gur-Cohen, Ph.D.
June 2, 2020 Thursday	“Cancer and cancer stem cells” Catriona Jamieson, M.D., Ph.D.	“Cancer Immunotherapies” Dan Kaufman, M.D., Ph.D.