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CMM 250 - Stem Cell Biology Core Course, Section 492943

 

Instructor: Karl Willert (kwillert@health.ucsd.edu) 858-822-3235

Program Administrator: Marci Murray (mjmurray@health.ucsd.edu) 858-534-7088

Student Assistant: Bethany Sawyer (basawyer@health.ucsd.edu)

 

The CMM 250 Stem Cell Biology Core Course provides the latest information in stem cell biology, medicine, and ethics. 

 

 

Course Description

This course provides the latest information in stem cell biology, medicine, and ethics. Ffaculty members from UC San Diego, the Salk Institute, the Sanford-Burnham-Prebys Institute, the Scripps Research Institute, and the La Jolla Institute of Allergy and Immunology

will give 1-hour lectures on the basic concepts of embryonic and adult stem cells, as well as on the ethical, legal, societal and political issues surrounding stem cell research and regenerative medicine. 

The course will be in-person only, with a few exceptions to accommodate speakers who are unable to attend. All students are required to attend in person. Only in the event that restrictions are imposed on in-person meetings, we will meet via Zoom at http://tinyurl.com/willertzoom. 

Scientific Lectures

Faculty speakers will present basic, translational and clinical research findings involving stem cells in human and model systems. Topics will include what is known about various stem cell populations; the identification, purification and properties of stem cells; possible and actual uses of stem cells in animal models of relevant diseases; possible and actual uses in clinical application to an organ system or disease state. Active participation is encouraged and will be a main criterion for grading. 

Course Requirements

Attendance

Attendance is mandatory. One excused absence will be allowed per quarter.

Participation 

Faculty lecturers will present topics in a manner that encourages student participation. Questions and comments are highly encouraged, and spontaneous contributions will be a major criterion for grading. 

 

 

Course Syllabus CMM 250 Section ID 492943, Spring 2024
DATE

8:30 am - 9:30 am

LECTURE TOPIC/LECTURER

9:30 am - 10:30 am

LECTURE TOPIC/LECTURER 

Week 1
April 2, 2024 Tuesday Course Introduction “Pluripotent stem cells” Karl Willert, Ph.D.

A brief personal overview of pluripotent stem cell science and politics” 

Larry Goldstein, Ph.D. (ZOOM)

April 4, 2024 Thursday 

“HSC Maintenance” 

Robert Signer, Ph.D.

Biomaterials to determine sex differences in cardiovascular disease 

Brian Aguado, Ph.D. (confirmed) 

Week 2
April 9, 2024  Tuesday

“Analyses of pluripotency substates” 

Louise Laurent, M.D., Ph.D.

“HSC Development”  

David Traver, Ph.D.

April 11, 2024 Thursday

“Cardiac Stem Cells” 

Farah Sheikh, Ph.D.

SoCal Stem Cell Consortium 

Andrew Yoo, Ph.D., Development Biology, Washington Univ in St. Louis (in Roth Auditorium) 

Week 3
April 16, 2024 Tuesday

 “Genome Engineering: A Primer” 

Prashant Mali, Ph.D. ZOOM 

 “Wnt signaling in stem cells” 

Karl Willert, Ph.D.

April 18, 2024 Thursday

“Stem cells and niche dynamics in tissue regeneration and cancer initiation.” 

Shiri Gur-Cohen, Ph.D.

“Imaging Technologies” 

Eric Ahrens, Ph.D.

Week 4
April 23, 2024 Tuesday

“Modeling eye diseases” 

Karl Wahlin, Ph.D.

“DNA Modifications and Their Biological Roles” 

Anjana Rao, Ph.D.

April 25, 2024 Thursday

“Modeling brain cancer using genetically engineered stem cells” 

Frank Furnari, Ph.D.

“Spermatogonial Stem Cells” 

Miles Wilkinson, Ph.D.

Week 5
April 30, 2024 Tuesday 

“Tissue Engineering” 

Adam Engler, Ph.D.

“Therapeutic Targeting of Cancer Stem Cells” 

Leslie Crews, Ph.D.

May 2, 2024 Thursday 

Generation of functional human brain organoids” 

Alysson Muotri, Ph.D.

“Stem cell ethics” 

Reuven Brandt, Ph.D.

Week 6
May 7, 2024 Tuesday 

The Many Facets of Stem Cells in Lung 

Xin Sun, Ph.D.

“Injectable biomaterials for regenerative engineering”   

Karen Christman, Ph.D.

May 9, 2024 Thursday

“Cancer Immunotherapies” 

Dan Kaufman, M.D., Ph.D.

SoCal Stem Cell Seminar, Sanford Seminar, Roth Auditorium

Benjamin Freedman, Ph.D.

Week 7
May 14, 2024 Tuesday

“Beta cell biology” 

Matt Wortham, Ph.D.

“Introduction to Patent Law” 

Anuja Mehta, Ph.D.

May 16, 2024 Thursday

“Epidermal stem cells” 

George Sen, Ph.D.

“Using Next-Generation Sequencing to Study Cellular Differentiation and Reprogramming” 

Sven Heinz, Ph.D.

Week 8
May 21, 2024 Tuesday

“Immunologic Consequences of Cellular Reprogramming Processes"

  Gerald Morris, M.D.

“Stem cells to the rescue: Saving the northern white rhino from extinction” 

Marisa Korody, Ph.D.

May 23, 2024 Thursday

“Stem Cells in Spinal Cell- Replacement-Based Therapies”  

Martin Marsala, M.D.

“Stem cells, gene therapy and cystinosis” 

Stephanie Cherqui, Ph.D.

Week 9
May 28, 2024 Tuesday 

“Growing human organs” Juan Carlos Izpizua Belmonte, Ph.D.

“Introduction to stem cell ethics” 

Reuven Brandt, Ph.D. 

May 30, 2024 Thursday 

“Trophoblast stem cells and placental development” 

Francesca Soncin, Ph.D.

“Title TBD” 

Jerome Mertens

Week 10
June 4, 2024 Tuesday 

Stem cell modeling in neuroimmunology” 

Nicole Coufal, M.D., Ph.D.

“Liver and Regeneration” 

David Brenner, M.D. 

June 6, 2024 Thursday

Regeneration of sensory function in planarians 

Ricardo Zayas, Ph.D.

“Cancer and cancer stem cells” 

Catriona Jamieson, M.D., Ph.D.